Persistence and innovation effects in genetic and environmental factors in negative emotionality during infancy: A twin study /L. Schumann, M. Boivin, S. Paquin [et.al.]

Электронный ресурс
Другой Автор
Schumann, Lyndall
Paquin, Stéphane
Lacourse, Eric
Brendgen, Mara
Vitaro, Frank
Dionne, Ginette
Tremblay, Richard E.
Booij, Linda
Boivin, Michel
Источник
PLoS ONE 2017 Vol. 12, № 4. P. e0176601 (1-16)
Аннотация
Background Difficult temperament in infancy is a risk factor for forms of later internalizing and externalizing psychopathology, including depression and anxiety. A better understanding of the roots of difficult temperament requires assessment of its early development with a genetically informative design. The goal of this study was to estimate genetic and environmental contributions to individual differences in infant negative emotionality, their persistence over time and their influences on stability between 5 and 18 months of age. Method Participants were 244 monozygotic and 394 dizygotic twin pairs (49.7% male) recruited from birth. Mothers rated their twins for negative emotionality at 5 and 18 months. Longitudinal analysis of stability and innovation between the two time points was performed in Mplus. Results There were substantial and similar heritability (approximately 31%) and shared environmental (57.3%) contributions to negative emotionality at both 5 and 18 months. The trait’s interindividual stability across time was both genetically- and environmentally- mediated. Evidence of innovative effects (i.e., variance at 18 months independent from variance at 5 months) indicated that negative emotionality is developmentally dynamic and affected by persistent and new genetic and environmental factors at 18 months. Conclusions In the first two years of life, ongoing genetic and environmental influences support temperamental negative emotionality but new genetic and environmental factors also indicate dynamic change of those factors across time. A better understanding of the source and timing of factors on temperament in early development, and role of sex, could improve efforts to prevent related psychopathology.
Всего оценка: 0
Нет записей для отображения.
 
 
 
03358nab a2200409 c 4500
001
 
 
vtls000620983
003
 
 
RU-ToGU
005
 
 
20180209070200.0
007
 
 
cr |
008
 
 
180208|2017    xxu     s         a eng d
024
7
$a 10.1371/journal.pone.0176601 $2 doi
035
$a to000620983
039
9
$a 201802090702 $b cat202 $c 201802081656 $d VLOAD $y 201802081635 $z VLOAD
040
$a RU-ToGU $b rus $c RU-ToGU
245
1
0
$a Persistence and innovation effects in genetic and environmental factors in negative emotionality during infancy: A twin study $c L.  Schumann, M.  Boivin, S.  Paquin [et.al.]
504
$a Библиогр.: 59 назв.
520
3
$a Background Difficult temperament in infancy is a risk factor for forms of later internalizing and externalizing psychopathology, including depression and anxiety. A better understanding of the roots of difficult temperament requires assessment of its early development with a genetically informative design. The goal of this study was to estimate genetic and environmental contributions to individual differences in infant negative emotionality, their persistence over time and their influences on stability between 5 and 18 months of age. Method Participants were 244 monozygotic and 394 dizygotic twin pairs (49.7% male) recruited from birth. Mothers rated their twins for negative emotionality at 5 and 18 months. Longitudinal analysis of stability and innovation between the two time points was performed in Mplus. Results There were substantial and similar heritability (approximately 31%) and shared environmental (57.3%) contributions to negative emotionality at both 5 and 18 months. The trait’s interindividual stability across time was both genetically- and environmentally- mediated. Evidence of innovative effects (i.e., variance at 18 months independent from variance at 5 months) indicated that negative emotionality is developmentally dynamic and affected by persistent and new genetic and environmental factors at 18 months. Conclusions In the first two years of life, ongoing genetic and environmental influences support temperamental negative emotionality but new genetic and environmental factors also indicate dynamic change of those factors across time. A better understanding of the source and timing of factors on temperament in early development, and role of sex, could improve efforts to prevent related psychopathology.
653
$a близнецовые исследования
653
$a младенчество
653
$a негативная эмоциональность
653
$a темперамент
655
4
$a статьи в журналах
700
1
$a Schumann, Lyndall
700
1
$a Paquin, Stéphane
700
1
$a Lacourse, Eric
700
1
$a Brendgen, Mara
700
1
$a Vitaro, Frank
700
1
$a Dionne, Ginette
700
1
$a Tremblay, Richard E.
700
1
$a Booij, Linda
700
1
$a Boivin, Michel
773
0
$t PLoS ONE $d 2017 $g Vol. 12, № 4. P. e0176601 (1-16) $x 1932-6203
852
4
$a RU-ToGU
856
7
$u http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000620983
908
$a статья
999
$a VIRTUA               
999
$a VTLSSORT0010*0030*0050*0070*0080*0240*0350*0390*0400*2450*5040*5200*6530*6531*6532*6533*6550*7000*7008*7001*7002*7003*7004*7005*7006*7007*7730*8520*8560*9080*9992
Нет комментариев.
Предмет
статьи в журналах
Резюме
Background Difficult temperament in infancy is a risk factor for forms of later internalizing and externalizing psychopathology, including depression and anxiety. A better understanding of the roots of difficult temperament requires assessment of its early development with a genetically informative design. The goal of this study was to estimate genetic and environmental contributions to individual differences in infant negative emotionality, their persistence over time and their influences on stability between 5 and 18 months of age. Method Participants were 244 monozygotic and 394 dizygotic twin pairs (49.7% male) recruited from birth. Mothers rated their twins for negative emotionality at 5 and 18 months. Longitudinal analysis of stability and innovation between the two time points was performed in Mplus. Results There were substantial and similar heritability (approximately 31%) and shared environmental (57.3%) contributions to negative emotionality at both 5 and 18 months. The trait’s interindividual stability across time was both genetically- and environmentally- mediated. Evidence of innovative effects (i.e., variance at 18 months independent from variance at 5 months) indicated that negative emotionality is developmentally dynamic and affected by persistent and new genetic and environmental factors at 18 months. Conclusions In the first two years of life, ongoing genetic and environmental influences support temperamental negative emotionality but new genetic and environmental factors also indicate dynamic change of those factors across time. A better understanding of the source and timing of factors on temperament in early development, and role of sex, could improve efforts to prevent related psychopathology.