Noncontact phase-sensitive dynamic optical coherence elastography at megahertz rate /M. Singh, C. Wu, C. Liu [et.al.]

Электронный ресурс
Другой Автор
Singh, Manmohan
Liu, Chih-Hao
Li, Jiasong
Schill, Alexander
Nair, Achuth
Kistenev, Yury V.
Larin, Kirill V.
Wu, Chen
Источник
Proceedings of SPIE 2016 Vol. 9697 : Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX. P. 96970P-1-96970P-8
Аннотация
Dynamic optical coherence elastography (OCE) techniques have shown great promise at quantitatively obtaining the biomechanical properties of tissue. However, the majority of these techniques have required multiple temporal OCT acquisitions (M-B mode) and corresponding excitations, which lead to clinically unfeasible acquisition times and potential tissue damage. Furthermore, the large data sets and extended laser exposures hinder their translation to the clinic, where patient discomfort and safety are critical criteria. In this work we demonstrate noncontact true kilohertz frame-rate dynamic optical coherence elastography by directly imaging a focused air-pulse induced elastic wave with a home-built phase-sensitive OCE system based on a 4X buffered Fourier Domain Mode Locked swept source laser with an A-scan rate of ~1.5 MHz. The elastic wave was imaged at a frame rate of ~7.3 kHz using only a single excitation. In contrast to previous techniques, successive B-scans were acquired over the measurement region (B-M mode) in this work. The feasibility of this method was validated by quantifying the elasticity of tissue-mimicking agar phantoms as well as porcine corneas ex vivo at different intraocular pressures. The results demonstrate that this method can acquire a depth-resolved elastogram in milliseconds. The reduced data set enabled a rapid elasticity assessment, and the ultra-fast acquisition speed allowed for a clinically safe laser exposure to the cornea. © (2016) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Всего оценка: 0
Нет записей для отображения.
 
 
 
03210nab a2200397 c 4500
001
 
 
vtls000553761
003
 
 
RU-ToGU
005
 
 
20190120213500.0
007
 
 
cr |
008
 
 
190120|2016    xxu     s         a eng d
024
7
$a 10.1117/12.2208404 $2 doi
035
$a to000553761
039
9
$a 201901202135 $b staff $c 201901131855 $d staff $c 201612270819 $d cat202 $c 201612231407 $d VLOAD $y 201612231219 $z VLOAD
040
$a RU-ToGU $b rus $c RU-ToGU
245
1
0
$a Noncontact phase-sensitive dynamic optical coherence elastography at megahertz rate $c M.  Singh, C.  Wu, C.  Liu [et.al.]
504
$a Библиогр.: 43 назв.
520
3
$a Dynamic optical coherence elastography (OCE) techniques have shown great promise at quantitatively obtaining the biomechanical properties of tissue. However, the majority of these techniques have required multiple temporal OCT acquisitions (M-B mode) and corresponding excitations, which lead to clinically unfeasible acquisition times and potential tissue damage. Furthermore, the large data sets and extended laser exposures hinder their translation to the clinic, where patient discomfort and safety are critical criteria. In this work we demonstrate noncontact true kilohertz frame-rate dynamic optical coherence elastography by directly imaging a focused air-pulse induced elastic wave with a home-built phase-sensitive OCE system based on a 4X buffered Fourier Domain Mode Locked swept source laser with an A-scan rate of ~1.5 MHz. The elastic wave was imaged at a frame rate of ~7.3 kHz using only a single excitation. In contrast to previous techniques, successive B-scans were acquired over the measurement region (B-M mode) in this work. The feasibility of this method was validated by quantifying the elasticity of tissue-mimicking agar phantoms as well as porcine corneas ex vivo at different intraocular pressures. The results demonstrate that this method can acquire a depth-resolved elastogram in milliseconds. The reduced data set enabled a rapid elasticity assessment, and the ultra-fast acquisition speed allowed for a clinically safe laser exposure to the cornea. © (2016) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
653
$a эластография
653
$a роговица глаза
653
$a эластичность
653
$a лазерные воздействия
655
4
$a статьи в журналах
700
1
$a Singh, Manmohan
700
1
$a Liu, Chih-Hao
700
1
$a Li, Jiasong
700
1
$a Schill, Alexander
700
1
$a Nair, Achuth
700
1
$a Kistenev, Yury V.
700
1
$a Larin, Kirill V.
700
1
$a Wu, Chen
773
0
$t Proceedings of SPIE $d 2016 $g Vol. 9697 : Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX. P. 96970P-1-96970P-8 $x 0277-786X
852
4
$a RU-ToGU
856
7
$u http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000553761
908
$a статья
999
$a VIRTUA
999
$a VTLSSORT0010*0030*0050*0070*0080*0240*0350*0390*0400*2450*5040*5200*6530*6531*6532*6533*6550*7000*7007*7001*7002*7003*7004*7005*7006*7730*8520*8560*9080*9992
Нет комментариев.
Предмет
статьи в журналах
Резюме
Dynamic optical coherence elastography (OCE) techniques have shown great promise at quantitatively obtaining the biomechanical properties of tissue. However, the majority of these techniques have required multiple temporal OCT acquisitions (M-B mode) and corresponding excitations, which lead to clinically unfeasible acquisition times and potential tissue damage. Furthermore, the large data sets and extended laser exposures hinder their translation to the clinic, where patient discomfort and safety are critical criteria. In this work we demonstrate noncontact true kilohertz frame-rate dynamic optical coherence elastography by directly imaging a focused air-pulse induced elastic wave with a home-built phase-sensitive OCE system based on a 4X buffered Fourier Domain Mode Locked swept source laser with an A-scan rate of ~1.5 MHz. The elastic wave was imaged at a frame rate of ~7.3 kHz using only a single excitation. In contrast to previous techniques, successive B-scans were acquired over the measurement region (B-M mode) in this work. The feasibility of this method was validated by quantifying the elasticity of tissue-mimicking agar phantoms as well as porcine corneas ex vivo at different intraocular pressures. The results demonstrate that this method can acquire a depth-resolved elastogram in milliseconds. The reduced data set enabled a rapid elasticity assessment, and the ultra-fast acquisition speed allowed for a clinically safe laser exposure to the cornea. © (2016) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.