Bioactivity and physico-chemical properties of composites on basis of hydroxyapatite with lactic and glycolic acids oligomers /L. A. Rasskazova, D. N. Lytkina, Y. G. Shapovalova [et.al.]

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Другой Автор
Rasskazova, Lyudmila A.
Shapovalova, Yelena G.
Botvin, Vladimir V.
Pozdnyakov, Maksim A.
Zhuk, Ilya V.
Filimoshkin, Anatoliy G.
Korotchenko, Natalya M.
Kozik, Vladimir V.
Lytkina, Darya N.
Источник
Advanced Materials Research 2015 Vol. 1085. P. 394-399
Аннотация
A new method in situ for producing of biocompatible composites based on hydroxyapatite and oligomers of lactic and glycolic acid is described. Their thermo-mechanical, physical-chemical and biological properties are studied as well. The formation of bonds between hydroxyapatite with lactic and glycolic oligomers in composites are confirmed by IR spectroscopy of the samples, including those obtained in the Soxhlet apparatus. The formation of calciumphosphate layer on the surface of composite containing hydroxyapatite was shown by SBFinvestigation. The scaffolds based on lactic acid oligomer do not stimulate formation of a calciumphosphate layer and they are subjected to destruction by the way of hydrolysis.
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Предмет
статьи в журналах
Резюме
A new method in situ for producing of biocompatible composites based on hydroxyapatite and oligomers of lactic and glycolic acid is described. Their thermo-mechanical, physical-chemical and biological properties are studied as well. The formation of bonds between hydroxyapatite with lactic and glycolic oligomers in composites are confirmed by IR spectroscopy of the samples, including those obtained in the Soxhlet apparatus. The formation of calciumphosphate layer on the surface of composite containing hydroxyapatite was shown by SBFinvestigation. The scaffolds based on lactic acid oligomer do not stimulate formation of a calciumphosphate layer and they are subjected to destruction by the way of hydrolysis.